Take exit 134 (if you miss it, you can also take exit 133), the Arthur Street exit. Once you take the exit, you are immediately on Arthur Street.  Continue straight along Arthur Street, through a stop sign and a traffic light, until it dead-ends into Eastern Parkway. Turn right onto Eastern Parkway. You are heading west. Follow Eastern parkway over a bridge and through a slight jog left until Eastern dead-ends into 3rd Street. (3rd Street is the second traffic light on Eastern Parkway). Turn right onto 3rd Street and take the first right into the circle drive at the main gates of the University. About 1/3 of the way around the drive is a Visitor Information Center followed by the entrance to a parking lot. Drive up to the window of the Visitor Information Center and obtain a parking permit. They will tell you where to park and can give you directions to the Natural Science Building.